PrimeMaxTM siRNA CPG
Prime Performance. Maximum Yield.
Introducing a new era of controlled-pore glass (CPG) solid supports designed to maximise efficiency and yields, enabling scalable, sustainable therapeutic oligo synthesis at lower costs.
Now available as catalogue products. View options →
Why choose PrimeMax CPG?
NexGen Native CPG Manufacturing
- Significantly reduced processing time (2 weeks) and energy use with removal of heating
- Production capacity increased by 200%
- Waste-water volume reduced by 50%
| New processes better suited to scale-up allowing us to grow economically with customer demand, whilst reducing cost and environmental impact. |
Surface Area Normalised Loading (SANL) Optimisation
- Improved synthesis efficiency, with reduced prevalence of early coupling failures
| Consistently increased yields. 15-30% increase in Net Full-Length Product (FLP) Yield for siRNA compared to existing products. |
Pore Size Optimisation
- Lower pore diameter CPGs designed to minimal level for specific oligos offer higher surface area and increased loading
potential - Optimised with SANL for specific modalities
| Maximises synthesis scale in your asset. |
New Capping Process
- New “end-capped” residual silanol processes reduce 3’ deletions and overall close-running impurities.
|
Higher yield and purity. Increased stability to DMT loss. |
PrimeMax siRNA CPG delivers higher productivity & yield in your asset.
*Minimum average gains vs Incumbent Product (600 Å CPG, 80-90 mmol/g)
Now available as catalogue products
PrimeMax siRNA CPG is now available as ready-to-order catalogue products, offering convenient access to high-quality CPG for oligonucleotide synthesis.
| Product name | Catalogue number |
| rA (Bz), 2'-OMe PrimeMax siRNA CPG, 400 Å | BG8-9001-B |
| rC (Ac), 2'-OMe PrimeMax siRNA CPG, 400 Å | BG8-9002-B |
| rG (iBu), 2'-OMe PrimeMax siRNA CPG, 400 Å |
BG8-9003-B |
| rU 2'-OMe PrimeMax siRNA CPG, 400 Å | BG8-9004-B |
| dT PrimeMax siRNA CPG, 400 Å | BG8-9005-B |
| UnyLinker™ PrimeMax siRNA CPG, 400 Å | BG8-9006-B |
| 3'-PT-Amino-C6 PrimeMax siRNA CPG, 400 Å | BG8-9007-B |
Custom options available
PrimeMax CPG offers a range of custom options to meet the specific needs of your oligonucleotide synthesis projects.
With custom PrimeMax CPG, you can:
Select the optimal pore size for your oligonucleotide length and chemistry
Choose linker types and modifications to meet your project requirements
Access unique functionalizations for specialized applications
Receive products manufactured to the same high standards as our catalogue offerings
Our custom CPG solutions provide the flexibility, precision, and control needed for advanced oligonucleotide synthesis.
