DNA encoded libraries brochure

Accelerating drug discovery for definitive results

With more than 10 years of experience in large scale manufacturing of synthetic DNA for DNA encoded libraries (DEL), our oligos remain unmatched in their quality and purity to help our customers:

  • Minimize impurities in the libraries
  • Increase library yield
  • Increase ligation efficiencies 
  • Maximize data reproducibility

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“I have been working in the DNA encoded library field for many years and have tried multiple suppliers for our synthetic DNA in the past. By far, nobody has surpassed the quality and commitment from Biosearch, allowing us to synthesis our libraries with the highest fidelity.”

- Paolo Centrella
Associate Director, Discovery Chemistry, X-Chem Inc.

In this brochure, you will learn how we enable our customers to build better libraries, maintain high purity and yields, and create customisations according to their specific needs.

 

Discover our full selection of headpieces, tags, primers, tailpieces and enzymes that support DEL synthesis.

Top citations

A Handbook for DNA-Encoded Chemistry: Theory and Applications for Exploring Chemical Space and Drug Discovery. Ed.: Goodnow RA, Jr. (2014) John Wiley & Sons, Inc. ISBN: 978-1-118-83267-7

 

Recent advances on the encoding and selection methods of DNA-encoded chemical library

Bingbing Shi et al. Bioorg Med Chem Lett. 2017.

 

DNA-encoded library-derived DDR1 inhibitor prevents fibrosis and renal function loss in a genetic mouse model of Alport syndrome

Hans Richter et al. ACS Chem. Biol. 2018.